The Science Behind Ivermectin: Evidence-Based, Idaho-Made, Prescription-Free

Idamectin is Idaho’s premier legal, over-the-counter human-grade ivermectin, formulated specifically for human use and rigorously tested.

Empowering Idahoans with Real Information

This page is designed to provide you with clear, factual information about our ingredients, why they’re included, and the scientific data about their safety. At Idamectin, we support your right to make informed, independent decisions about your health—rooted in science and protected by Idaho law.

Disclaimer: All information contained on this page is for information purposes only and is not to be substituted for medical advice. We recommend consulting with a healthcare professional.
3D model of a biological membrane with molecular structures interacting on a blue background

General Educational Information

Ivermectin is an anthelmintic, meaning it works to kill or expel parasitic worms from the body. Its primary mechanism of action involves interfering with the nervous and muscular systems of these parasites.

Ivermectin binds selectively and with high affinity to glutamate-gated chloride ion channels that are present in the nerve and muscle cells of parasitic worms.

Diagram of muscle cells and nerve cells with labels on a gray background

Increases Chloride Permeability: This binding causes these channels to open and significantly increases the permeability of the parasite's cell membranes to chloride ions.

Hyperpolarization: The influx of chloride ions leads to a state called hyperpolarization of the parasite's nerve or muscle cells. This means the cell's electrical potential becomes more negative than its resting state.

Paralysis and Death: This hyperpolarization inhibits neural transmission, effectively paralyzing the parasite. The paralysis prevents the parasite from feeding, moving, or reproducing, ultimately leading to its death.

What about Fenbendazole?

Fenbendazole is a broad-spectrum anthelmintic (anti-parasitic) medication primarily used to treat various parasitic worms. It belongs to a class of drugs called benzimidazoles.

Its primary mechanism of action against parasites involves disrupting their microtubule formation and function. Here's a more detailed breakdown:

  • Binding to Beta-Tubulin: Fenbendazole works by selectively binding to beta-tubulin within the cells of parasites. Tubulin is a crucial protein that forms microtubules, which are essential components of a cell's cytoskeleton.
  • Inhibiting Microtubule Formation: By binding to beta-tubulin, fenbendazole prevents the parasites from properly forming and assembling their microtubules.

Its primary mechanism of action against parasites involves disrupting their microtubule formation and function. Here's a more detailed breakdown:

  • Impaired Cell Division

    Microtubules are vital for cell division (mitosis). Without properly formed microtubules, parasitic cells cannot divide effectively, hindering their growth and reproduction.

  • Inhibition of Nutrient Uptake

    Microtubules are also involved in the transport of nutrients within the parasite's cells. Their disruption prevents the parasite from absorbing essential nutrients, effectively starving it.

  • Loss of Mobility and Secretion

    Microtubules are important for the motility and secretory processes of cells. Their disruption can paralyze the parasite and hinder its ability to secrete waste products.

Energy Depletion and Parasite Death: The overall disruption of these vital cellular functions inhibits the parasite's ability to produce energy, leading to its paralysis and eventual death.

Illustration of immune cells attacking cancer cells with arrows indicating the process.

Cancer Fighter?

While primarily known for its antiparasitic effects, there has been research into fenbendazole's potential as an anticancer drug due to its ability to disrupt microtubules, similar to some chemotherapy agents. However, this is an area of ongoing research, and it is not currently approved for human cancer treatment. You can read more about the case study here.

Ivermectin and Fenbendazole have been a focus of ongoing scientific research for their broad-spectrum activity.

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6mg Ivermectin in every capsule (and 111mg Fenbendazole in Idamectin Plus)
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